Hyaluronidase treatment at Arvé Aesthetics in Greenville, SC offers a safe, reliable method for reversing hyaluronic acid-based dermal fillers. Whether results have not met expectations, filler has migrated, or a complication has developed, enzymatic dissolving allows the tissue to be returned to its natural state with precision and appropriate medical oversight.
What is Hyaluronidase?
Hyaluronidase is an enzyme that breaks down hyaluronic acid, the primary component of most modern dermal fillers. The enzyme occurs naturally in the body and works by cleaving the HA chains within the filler, causing it to dissolve and be reabsorbed by the surrounding tissue. When injected directly into the area of concern, hyaluronidase acts quickly, with visible changes typically beginning within hours and full resolution apparent within 24 to 48 hours.
Because hyaluronidase targets only hyaluronic acid, it is effective for dissolving HA-based fillers including those in the Juvederm, Restylane, and Evolysse product lines. It does not affect non-HA injectables such as Bellafill or Radiesse.
What It Addresses
Hyaluronidase treatment may be appropriate when:
- Unsatisfactory results: the outcome of a prior filler treatment does not align with the patient’s aesthetic goals
- Filler migration: product has shifted from the original placement site, creating an uneven or unnatural appearance
- Overcorrection: the volume or projection achieved exceeds what was intended or desired Asymmetry: uneven distribution of filler that has not resolved on its own
- Complications: including vascular compromise, nodules, or inflammatory reactions requiring prompt intervention
- Preparation for retreatment: complete or partial removal of existing filler to allow for a fresh approach to treatment planning
What to Expect
Consultation
A consultation with one of our providers is required before treatment. The provider will evaluate the area of concern, assess the type and estimated volume of filler present, and determine the appropriate dose and injection plan. Patients who received their original filler treatment at another practice are encouraged to bring any records indicating the product used, as this information supports accurate planning.
The Procedure
Treatment is performed in a private, closed-door room. The area is cleansed and a topical numbing agent is applied prior to injection. Hyaluronidase is then administered directly into the targeted tissue using precise, anatomy-guided technique. The number of injection points and total dose used will depend on the volume of filler present and the extent of correction needed. Most patients notice softening of the treated area within a short time following the injections.
Duration
Most appointments take approximately 30 to 45 minutes from start to finish, including preparation and post-treatment assessment.
Results
Initial changes are typically visible within a few hours of treatment. Full resolution of the filler is generally apparent within 24 to 48 hours. A follow-up appointment is scheduled to assess the outcome and determine whether any additional dissolving is needed or whether the patient wishes to discuss retreatment options.
How Many Treatments Are Needed?
Most patients achieve adequate dissolution in a single session. Cases involving larger volumes of filler, older or more cross-linked product, or deeper tissue placement may require a second round of hyaluronidase to achieve complete resolution. This will be assessed at the follow-up appointment.
Who is Not a Good Candidate?
Hyaluronidase treatment may not be appropriate for patients who:
- Have a known allergy to hyaluronidase or bee stings: hymenoptera venom contains hyaluronidase, and a known allergy warrants careful evaluation before proceeding
- Have non-HA filler in the area: hyaluronidase will not dissolve Sculptra, Radiesse, silicone, or other non-HA products
- Have active infection in the treatment area: dissolving should be deferred until any active skin infection has resolved
- Are pregnant or breastfeeding: treatment is not recommended during pregnancy or lactation
- Have unrealistic expectations about retreatment: patients should understand that dissolving restores the tissue to its pre-filler baseline and does not guarantee a specific outcome if retreatment is pursued
Aftercare
Following hyaluronidase treatment:
- Expect temporary swelling and redness: mild inflammatory response at the injection site is normal and typically resolves within 24 hours
- Avoid touching or massaging the area: the tissue is in an active state of change immediately following treatment; manipulation is not necessary and should be avoided
- Stay well hydrated: adequate hydration supports normal tissue recovery
- Avoid heat and strenuous activity: saunas, hot tubs, and vigorous exercise should be avoided for 24 hours following treatment
- Attend the scheduled follow-up: the follow-up appointment is an essential part of the process and allows the provider to assess the degree of dissolution and discuss next steps
- Allow adequate time before retreatment: if new filler is desired, a waiting period is typically recommended to allow the tissue to fully stabilize; timing will be discussed at the follow-up
Precision Over Volume
Hyaluronidase treatment at Arvé Aesthetics is approached with the same anatomical precision and clinical honesty that guides every injectable service at the practice. Whether the goal is correcting a prior result or preparing for a new treatment plan, patients can expect a thorough assessment and a clear path forward.
To schedule a consultation at Arvé Aesthetics in Greenville, SC, contact our team at (864) 696-2234 or use our online booking link.